Tanshinone IIA

Research use only, not for human use.

Tanshinone IIA(Tanshinone B) is the diterpene quinone in Danshen, which is utilized in the treatment of cardiovascular and inflammatory.

Tanshinone IIA(Tanshinone B) is the diterpene quinone in Danshen, which is utilized in the treatment of cardiovascular and inflammatory.

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Animal Model:Male ICR mice (25–30 g) Dosage:10 or 20 mg/kg Administration:P.o.Result:Significantly reversed scopolamine-induced cognitive impairments. Animal Model:STZ-treated rats Dosage:2, 4, 8 mg/kg Administration:I.p.Result:Decreased the expression levels of transforming growth factor-beta1, TSP-1, Grp78 and CHOP and attenuated the increase in the protein levels of p-PERK, p-elf2α and ATF-4 from the renal tissues of diabetic rats.Animal Model:Female Sprague-Dawley rats (180 -200g)Dosage:3 and 12 mg/kg Administration:I.p.Result:Significantly inhibited the growth of ectopic endometrium.

Dan Shen ketone

GPCR/G Protein

Histamine Receptor

VEGFR2

Cancer|Cardiovascular Disease

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568-72-9

294.35

C19H18O3

>98% (HPLC)

DMSO : 3.85 mg/mL 13.08 mM; H2O : < 0.1 mg/mL

c12c(C(=O)C(=O)c3c1ccc1c3CCCC1(C)C)c(co2)C

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(-20℃)

With Ice Pack

≥ 2 years