Cart
sales@molnova.com
Folinic acid
CAS No. 58-05-9
Folinic acid( —— )
Catalog No. M33999 CAS No. 58-05-9
Folinic acid (Leucovorin) is a biofolate used in the treatment of methotrexate (MTX) toxicity reduction and as an adjuvant therapy for colon cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 31 | In Stock |
|
| 25MG | 46 | In Stock |
|
| 50MG | 64 | In Stock |
|
| 100MG | 90 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 215 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameFolinic acid
-
NoteResearch use only, not for human use.
-
Brief DescriptionFolinic acid (Leucovorin) is a biofolate used in the treatment of methotrexate (MTX) toxicity reduction and as an adjuvant therapy for colon cancer.
-
DescriptionFolinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity.
-
In Vitro——
-
In VivoAnimal Model:24 Balb/c young growing male mice aged 3 weeks (11.88 ± 0.25 g)Dosage:7.0 mg/kg Administration:Intraperitoneal injection; every second day; for 3 weeks Result:Following MTX administration appears to reverse this growth inhibition.
-
Synonyms——
-
PathwayProteasome/Ubiquitin
-
TargetEndogenous Metabolite
-
RecptorEndogenous Metabolite | Antifolate
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number58-05-9
-
Formula Weight473.44
-
Molecular FormulaC20H23N7O7
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (528.05 mM; Ultrasonic )
-
SMILESNc1nc2NCC(CNc3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)N(C=O)c2c(=O)[nH]1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Keshava, C., et al., Inhibition of methotrexate-induced chromosomal damage by folinic acid in V79 cells. Mutat Res, 1998. 397(2): p. 221-8.?
molnova catalog
related products
-
Ochratoxin B
Ochratoxin B is produced by a variety of Aspergillus and Penicillium species and is an analog of the mycotoxin Ochratoxin A, which can contaminate agricultural products.
-
Magnesium acetate te...
Magnesium acetate tetrahydrate is the hydrated form of the anhydrous magnesium acetate salt.Magnesium acetate tetrahydrate is commonly used to synthesize other compounds, cocoa as an electrolyte supplement or as a reagent in molecular biology experiments.
-
Mannan
Mannan is isolated from algae, mushrooms, yeast and higher plants and acts as an immunomodulator.
