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(Z)-FeCP-oxindole
CAS No. 1137967-28-2
(Z)-FeCP-oxindole( —— )
Catalog No. M33952 CAS No. 1137967-28-2
(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for humans and demonstrates anticancer activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | In Stock |
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| 10MG | 49 | In Stock |
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| 25MG | 93 | In Stock |
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| 50MG | 148 | In Stock |
|
| 100MG | 226 | In Stock |
|
| 200MG | 318 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(Z)-FeCP-oxindole
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NoteResearch use only, not for human use.
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Brief Description(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for humans and demonstrates anticancer activity.
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Description(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetVEGFR
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RecptorVEGFR
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Research Area——
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Indication——
Chemical Information
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CAS Number1137967-28-2
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Formula Weight329.17
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Molecular FormulaC19H15FeNO
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (151.90 mM; Ultrasonic )
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SMILESC(\[C-]12[Fe+2]3456789([CH]1=[CH]3[CH]4=[CH]52)[CH-]%10[CH]6=[CH]7[CH]8=[CH]9%10)=C\%11/C=%12C(NC%11=O)=CC=CC%12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. John Spencer, et al. Synthesis and evaluation of metallocene containing methylidene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors. Metallomics. 2011 Jun;3(6):600-8.?
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