GSK J5( —— )

Catalog No. M33860 CAS No. 1394854-51-3

GSK J5 is an inhibitor of schistosomes and helminths and is often used as a trematode insecticide.GSK J5 promotes schistosome mortality in a dose- and time-dependent manner.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	113	In Stock
5MG	122	In Stock
10MG	202	In Stock
25MG	448	In Stock
50MG	641	In Stock
100MG	914	In Stock
200MG	Get Quote	In Stock
500MG	1832	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

GSK J5
Note

Research use only, not for human use.
Brief Description

GSK J5 is an inhibitor of schistosomes and helminths and is often used as a trematode insecticide.GSK J5 promotes schistosome mortality in a dose- and time-dependent manner.
Description

GSK-J5 is a potent inhibitor of Schistosome and worm. GSK-J5 increases schistosomula mortality and adult worm motility and mortality, as well as egg oviposition, in a dose- and time-dependent manner.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

Histone Demethylase
Recptor

Histone Demethylase
Research Area

——
Indication

——

Chemical Information

CAS Number

1394854-51-3
Formula Weight

417.5
Molecular Formula

C24H27N5O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (299.40 mM; Ultrasonic )
SMILES

N(CCC(OCC)=O)C1=CC(=NC(=N1)C=2C=CC=NC2)N3CCC=4C(CC3)=CC=CC4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kruidenier L, et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature. 2012 Aug 16;488(7411):404-8.?

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