GSK J5( —— )

Catalog No. M33860 CAS No. 1394854-51-3

GSK J5 is an inhibitor of schistosomes and helminths and is often used as a trematode insecticide.GSK J5 promotes schistosome mortality in a dose- and time-dependent manner.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

GSK J5
Note

Research use only, not for human use.
Brief Description

GSK J5 is an inhibitor of schistosomes and helminths and is often used as a trematode insecticide.GSK J5 promotes schistosome mortality in a dose- and time-dependent manner.
Description

GSK-J5 is a potent inhibitor of Schistosome and worm. GSK-J5 increases schistosomula mortality and adult worm motility and mortality, as well as egg oviposition, in a dose- and time-dependent manner.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

Histone Demethylase
Recptor

Histone Demethylase
Research Area

——
Indication

——

Chemical Information

CAS Number

1394854-51-3
Formula Weight

417.5
Molecular Formula

C24H27N5O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (299.40 mM; Ultrasonic )
SMILES

N(CCC(OCC)=O)C1=CC(=NC(=N1)C=2C=CC=NC2)N3CCC=4C(CC3)=CC=CC4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kruidenier L, et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature. 2012 Aug 16;488(7411):404-8.?

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