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Home - Products - Chromatin/Epigenetic - Histone Demethylase - GSK J5

GSK J5

CAS No. 1394854-51-3

GSK J5( —— )

Catalog No. M33860 CAS No. 1394854-51-3

GSK J5 is an inhibitor of schistosomes and helminths and is often used as a trematode insecticide.GSK J5 promotes schistosome mortality in a dose- and time-dependent manner.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 113 In Stock
5MG 122 In Stock
10MG 202 In Stock
25MG 448 In Stock
50MG 641 In Stock
100MG 914 In Stock
200MG Get Quote In Stock
500MG 1832 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    GSK J5
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK J5 is an inhibitor of schistosomes and helminths and is often used as a trematode insecticide.GSK J5 promotes schistosome mortality in a dose- and time-dependent manner.
  • Description
    GSK-J5 is a potent inhibitor of Schistosome and worm. GSK-J5 increases schistosomula mortality and adult worm motility and mortality, as well as egg oviposition, in a dose- and time-dependent manner.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Histone Demethylase
  • Recptor
    Histone Demethylase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1394854-51-3
  • Formula Weight
    417.5
  • Molecular Formula
    C24H27N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (299.40 mM; Ultrasonic )
  • SMILES
    N(CCC(OCC)=O)C1=CC(=NC(=N1)C=2C=CC=NC2)N3CCC=4C(CC3)=CC=CC4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kruidenier L, et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature. 2012 Aug 16;488(7411):404-8.?
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