PF-06821497( —— )

Catalog No. M26370 CAS No. 1844849-10-0

PF-06821497 is a selective inhibitor of EZH2 with significant tumor growth inhibition.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

PF-06821497
Note

Research use only, not for human use.
Brief Description

PF-06821497 is a selective inhibitor of EZH2 with significant tumor growth inhibition.
Description

PF-06821497 is a selective inhibitor of EZH2 with significant tumor growth inhibition.(In Vivo):The tumor regression effect of PF-06821497 can be sustained for another 40 days.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

Histone Demethylase
Recptor

Apoptosis| Autophagy
Research Area

——
Indication

——

Chemical Information

CAS Number

1844849-10-0
Formula Weight

467.34
Molecular Formula

C22H24Cl2N2O5
Purity

>98% (HPLC)
Solubility

——
SMILES

CO[C@H](C1COC1)c1cc(Cl)c2CCN(Cc3c(OC)cc(C)[nH]c3=O)C(=O)c2c1Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Greim H, Saltmiras D, Mostert V, Strupp C. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015 Mar;45(3):185-208.

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