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Gavestinel sodium

CAS No. 153436-38-5

Gavestinel sodium( —— )

Catalog No. M33855 CAS No. 153436-38-5

Gavestinel (GV 150526) is a non-competitive NMDA receptor antagonist that is potent, selective and orally active.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 140 In Stock
25MG 236 In Stock
50MG 343 In Stock
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Biological Information

  • Product Name
    Gavestinel sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    Gavestinel (GV 150526) is a non-competitive NMDA receptor antagonist that is potent, selective and orally active.
  • Description
    Gavestinel (GV 150526A) is a potent, selective, orally active and non-competitive antagonist of NMDA receptor. Gavestinel binds to the glycine site of the NMDA receptor, with a pKi of 8.5. Gavestinel can be used for the research of acute ischemic stroke.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    iGluR
  • Recptor
    iGluR | NMDAR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    153436-38-5
  • Formula Weight
    397.19
  • Molecular Formula
    C18H11Cl2N2NaO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (251.77 mM; Ultrasonic )
  • SMILES
    O=C(NC1=CC=CC=C1)/C=C/C2=C(C([O-])=O)NC3=CC(Cl)=CC(Cl)=C23.[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fabio RD, et, al. Substituted indole-2-carboxylates as in vivo potent antagonists acting as the strychnine-insensitive glycine binding site. J Med Chem. 1997 Mar 14;40(6):841-50.?
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