Cart
sales@molnova.com
Isomangiferin
CAS No. 24699-16-9
Isomangiferin( —— )
Catalog No. M13720 CAS No. 24699-16-9
Isomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 126 | In Stock |
|
| 2MG | 59 | In Stock |
|
| 5MG | 93 | In Stock |
|
| 10MG | 155 | In Stock |
|
| 25MG | 262 | In Stock |
|
| 50MG | 369 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameIsomangiferin
-
NoteResearch use only, not for human use.
-
Brief DescriptionIsomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM.
-
DescriptionIsomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM, also blocks calcium channel; also effectively blocks the EphA4-dependent signaling in hippocampal neurons, reduces the EphA4 activity effectively in the hippocampus of APP/PS1 transgenic mice after oral administration, restores the impaired long-term potentiation in transgenic mouse models of AD.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMembrane Transporter/Ion Channel
-
TargetiGluR
-
RecptorAntiviral|Free radical scavengers
-
Research AreaInfection
-
Indication——
Chemical Information
-
CAS Number24699-16-9
-
Formula Weight422.3396
-
Molecular FormulaC19H18O11
-
Purity>98% (HPLC)
-
SolubilityDMSO: 10 mM （ < 1 mg/ml refers to the product slightly soluble or insoluble )
-
SMILESC1=C2C(=CC(=C1O)O)OC3=C(C2=O)C(=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O
-
Chemical Name4-beta-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.?Kang TH, et al. Eur J Pharmacol. 2002 Nov 22;455(1):27-34.
2.?Kang TH, et al. Life Sci. 2004 Dec 3;76(3):331-43.
3.?Fu AK, et al. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9959-64.
molnova catalog
related products
-
SYM 2081
SYM 2081 is a specific kainate receptor agonist with an IC50 value of 35 nM for [3H]-kainate binding. SYM 2081 depolarizes the muscle and reduces the EPSP amplitude.
-
TAT-GluA2 3Y
Inhibitor of AMPA receptor endocytosis. Induces increased hind paw withdrawal latencies following thermal and mechanical stimuli in rats. Also exhibits antinociceptive effects in a rat model of neuropathic pain. Rescues pentobarbital-induced memory retrieval deficits in a rat model of learning and memory.
-
PEPA
PEPA is an allosteric AMPA receptors modulator; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.
