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AMPA receptor modulator-1
CAS No. 2036074-41-4
AMPA receptor modulator-1( —— )
Catalog No. M32776 CAS No. 2036074-41-4
AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 257 | In Stock |
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| 5MG | 255 | In Stock |
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| 10MG | 374 | In Stock |
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| 25MG | 562 | In Stock |
|
| 50MG | 770 | In Stock |
|
| 100MG | 1051 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAMPA receptor modulator-1
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NoteResearch use only, not for human use.
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Brief DescriptionAMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.
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DescriptionAMPA receptor modulator-1 is a potent, orally active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetiGluR
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RecptoriGluR
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Research Area——
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Indication——
Chemical Information
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CAS Number2036074-41-4
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Formula Weight341.71
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Molecular FormulaC16H11ClF3NO2
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Purity>98% (HPLC)
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Solubility——
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SMILESO(C(F)(F)F)C1=C(C=2C=C3C(=C(C)C2)NC(=O)C3)C(Cl)=CC=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ravula S, et al. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8. ACS Med Chem Lett. 2018 Jul 13;9(8):821-826.?
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