AMPA receptor modulator-1( —— )

Catalog No. M32776 CAS No. 2036074-41-4

AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	257	In Stock
5MG	255	In Stock
10MG	374	In Stock
25MG	562	In Stock
50MG	770	In Stock
100MG	1051	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

AMPA receptor modulator-1
Note

Research use only, not for human use.
Brief Description

AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.
Description

AMPA receptor modulator-1 is a potent, orally active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

iGluR
Recptor

iGluR
Research Area

——
Indication

——

Chemical Information

CAS Number

2036074-41-4
Formula Weight

341.71
Molecular Formula

C16H11ClF3NO2
Purity

>98% (HPLC)
Solubility

——
SMILES

O(C(F)(F)F)C1=C(C=2C=C3C(=C(C)C2)NC(=O)C3)C(Cl)=CC=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Ravula S, et al. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8. ACS Med Chem Lett. 2018 Jul 13;9(8):821-826.?

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