Cart
sales@molnova.com
SKF96067
CAS No. 115607-61-9
SKF96067( —— )
Catalog No. M33500 CAS No. 115607-61-9
SKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 686 | In Stock |
|
| 10MG | 938 | In Stock |
|
| 25MG | 1444 | In Stock |
|
| 50MG | 1841 | In Stock |
|
| 100MG | 2325 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSKF96067
-
NoteResearch use only, not for human use.
-
Brief DescriptionSKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.
-
DescriptionSKF96067 is a reversible inhibitor of the gastric H+/K+-ATPase.
-
In VitroSKF96067 inhibits K+-stimulated ATPase activity competitively with respect to the activating action K+, with a Ki value of 0.39 ± 0.05 μM. SKF96067 also inhibits hydrogen ion transport. SKF96067 inhibits ATPase activity with an IC50 value of 60 ± 10 μM at pH 7.0, in the presence of 100 mM NaCl and 1 mM KCl.
-
In Vivo——
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetATPase
-
RecptorATPase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number115607-61-9
-
Formula Weight334.41
-
Molecular FormulaC21H22N2O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(C1=CN=C2C(OC)=CC=CC2=C1NC=3C=CC=CC3C)CCC
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Keeling DJ, et al. SK&F 96067 is a reversible, lumenally acting inhibitor of the gastric (H+ + K+)-ATPase. Biochem Pharmacol. 1991 Jun 21;42(1):123-30.?
molnova catalog
related products
-
Lycorine
Lycorine inhibits?protein synthesis and may inhibit?ascorbic acid?biosynthesis, although studies on the latter are controversial and inconclusive.
-
Bufalin
Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu.
-
Wilforine
Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants and is effective in treating idiopathic pulmonary fibrosis.
