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SKF96067
CAS No. 115607-61-9
SKF96067( —— )
Catalog No. M33500 CAS No. 115607-61-9
SKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 1398 | Get Quote |
|
| 50MG | 1822 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSKF96067
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NoteResearch use only, not for human use.
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Brief DescriptionSKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.
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DescriptionSKF96067 is a reversible inhibitor of the gastric H+/K+-ATPase.
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In VitroSKF96067 inhibits K+-stimulated ATPase activity competitively with respect to the activating action K+, with a Ki value of 0.39 ± 0.05 μM. SKF96067 also inhibits hydrogen ion transport. SKF96067 inhibits ATPase activity with an IC50 value of 60 ± 10 μM at pH 7.0, in the presence of 100 mM NaCl and 1 mM KCl.
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetATPase
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RecptorATPase
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Research Area——
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Indication——
Chemical Information
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CAS Number115607-61-9
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Formula Weight334.41
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Molecular FormulaC21H22N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=CN=C2C(OC)=CC=CC2=C1NC=3C=CC=CC3C)CCC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Keeling DJ, et al. SK&F 96067 is a reversible, lumenally acting inhibitor of the gastric (H+ + K+)-ATPase. Biochem Pharmacol. 1991 Jun 21;42(1):123-30.?
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