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Pelubiprofen
CAS No. 69956-77-0
Pelubiprofen( —— )
Catalog No. M33458 CAS No. 69956-77-0
Pelubiprofen is an orally active, non-steroidal anti-inflammatory agent, a selective cyclooxygenase-2 (COX-2) inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 73 | In Stock |
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| 25MG | 140 | In Stock |
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| 50MG | 222 | In Stock |
|
| 100MG | 352 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 821 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePelubiprofen
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NoteResearch use only, not for human use.
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Brief DescriptionPelubiprofen is an orally active, non-steroidal anti-inflammatory agent, a selective cyclooxygenase-2 (COX-2) inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.
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DescriptionPelubiprofen, an orally active and non-steroidal anti-inflammatory drug, is a member of the 2-arylpropionic acid family and has relatively selective effects on COX-2 activity. Pelubiprofen inhibits COX activity and the transforming growth factor-β activated kinase 1-IκB kinase β-NF-κB pathway, and has significant anti-inflammatory and analgesic effects.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX
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Research Area——
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Indication——
Chemical Information
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CAS Number69956-77-0
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Formula Weight258.31
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Molecular FormulaC16H18O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (387.13 mM; Ultrasonic )
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SMILESC(\C1=CC=C(C(C(O)=O)C)C=C1)=C\2/C(=O)CCCC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Hamaudol
Hamaudol is a chromone isolated from Saposhnikovia divaricata,has analgesic and anti-inflammary activities, it showed inhibitory activity on COX-1 and COX-2 activities with values of 0.30, 0.57 mM, respectively.The CHCl3 extract of the root of Angelica japonica showed high inhibitory activity against human gastric adenocarcinoma (MK-1) cell growth.
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Niflumic acid
Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
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6-paradol
6-paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants and exhibits a variety of biological activities including anti-cancer anti-inflammatory and anti-oxidative activitiesneuroprotective Effects.
