Nepafenac

CAS No. 78281-72-8

Nepafenac( AHR-9434 | AL-6515 )

Catalog No. M15955 CAS No. 78281-72-8

A nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-1 and COX-2 activity; a prodrug of amfenac.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 38 In Stock
25MG 33 In Stock
50MG 54 In Stock
100MG 91 In Stock
200MG Get Quote In Stock
500MG 221 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Nepafenac
  • Note
    Research use only, not for human use.
  • Brief Description
    A nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-1 and COX-2 activity; a prodrug of amfenac.
  • Description
    A nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-1 and COX-2 activity; a prodrug of amfenac.Other Indication Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AHR-9434 | AL-6515
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX-1|COX-2
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    78281-72-8
  • Formula Weight
    254.2839
  • Molecular Formula
    C15H14N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 32 mg/mL
  • SMILES
    O=C(N)CC1=CC=CC(C(C2=CC=CC=C2)=O)=C1N
  • Chemical Name
    Benzeneacetamide, 2-amino-3-benzoyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gamache DA, et al. Inflammation. 2000 Aug;24(4):357-70. 2. Singh RP, et al. Ophthalmology. 2017 Jun;124(6):776-785. 3. Abu Hussein NB, et al .J Ophthalmol. 2017;2017:3765253.
molnova catalog
related products
  • CAY10404

    CAY10404 is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSCLC cells, with analgesic, anti-inflammatory and anti-cancer activities.

  • Mofezolac

    Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000.

  • Sodium salicylate

    Sodium salicylate is a metabolite of acetylsalicylic acid, and functions by inhibiting NF-kB and reduces oxidative stress.