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Neurodazine

CAS No. 937807-66-4

Neurodazine( —— )

Catalog No. M33441 CAS No. 937807-66-4

Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.Neurodazine promotes differentiation by activating Wnt and Shh signaling.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
2MG 49 In Stock
5MG 78 In Stock
10MG 112 In Stock
25MG 183 In Stock
50MG 266 In Stock
100MG 393 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Neurodazine
  • Note
    Research use only, not for human use.
  • Brief Description
    Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.Neurodazine promotes differentiation by activating Wnt and Shh signaling.
  • Description
    Neurodazine is a neurogenic inducer, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways..
  • In Vitro
    Neurodazine (5 μM; 1-10 d) treatment induces the expression of neuron-specific markers in P19 cells.Neurodazine selectively suppresses astrocyte differentiation of P19 cells.Western Blot Analysis Cell Line:P19 cells Concentration:5 μM Incubation Time:1-10 days Result:Induced the expression of neuron-specific markers.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Wnt/Notch/Hedgehog
  • Target
    Wnt/beta/catenin
  • Recptor
    Wnt/beta-catenin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    937807-66-4
  • Formula Weight
    456.92
  • Molecular Formula
    C27H21ClN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (218.86 mM; Ultrasonic )
  • SMILES
    COc1ccc(cc1)-c1nc([nH]c1-c1ccc(OC)cc1)-c1ccc(o1)-c1cccc(Cl)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kim GH, et al. Imidazole-based small molecules that promote neurogenesis in pluripotent cells. Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9271-4.?
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