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β-Elemonic Acid
CAS No. 28282-25-9
β-Elemonic Acid( —— )
Catalog No. M18358 CAS No. 28282-25-9
Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are related to the MAPK signaling pathway, ROS activation and glutathione depletion in human A549 lung cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 76 | In Stock |
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| 5MG | 69 | In Stock |
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| 10MG | 112 | In Stock |
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| 25MG | 202 | In Stock |
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| 50MG | 296 | In Stock |
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| 100MG | 440 | In Stock |
|
| 200MG | 631 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product Nameβ-Elemonic Acid
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NoteResearch use only, not for human use.
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Brief DescriptionBeta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are related to the MAPK signaling pathway, ROS activation and glutathione depletion in human A549 lung cancer cells.
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DescriptionBeta-Elemonic acid exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are related to the MAPK signaling pathway, ROS activation and glutathione depletion in human A549 lung cancer cells. Beta-Elemonic acid exhibits prolyl endopeptidase inhibitory activities.
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In Vitroβ-elemonic acid (1, 3, 10, 20 μM; 24 hours) strongly induces human A549 lung cancer cell apoptosis in a dose- and time-dependent manner. β-elemonic acid (1, 3, 10, 20 μM; 24 hours) exerts potent cytotoxic effects on human NSCLC A549 cells in a dose-dependent manner. The IC50 value following a 24-h exposure to β-elemonic acid was 6.92 μM. β-elemonic acid (20 μM; 24 hours) results in a cell percentage of 58.01% in the G0/G1 phase. β-elemonic acid (1, 3, 10, 20 μM; 24 hours) inhibits phosphorylation of p42/44, MAPK/JNK and p38 in the A549 cells.
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In Vivo——
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Synonyms——
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PathwayWnt/Notch/Hedgehog
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TargetWnt/beta/catenin
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number28282-25-9
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Formula Weight454.69
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Molecular FormulaC30H46O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (54.98 mM)
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SMILESCC(=CCCC(C1CCC2(C1(CCC3=C2CCC4C3(CCC(=O)C4(C)C)C)C)C)C(=O)O)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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