EGTA-AM( —— )

Catalog No. M33213 CAS No. 99590-86-0

EGTA-AM (EGTA Acetoxymethyl ester) is a calcium chelator, a metabolic biomarker of early-onset preeclampsia and late-onset preeclampsia.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

EGTA-AM
Note

Research use only, not for human use.
Brief Description

EGTA-AM (EGTA Acetoxymethyl ester) is a calcium chelator, a metabolic biomarker of early-onset preeclampsia and late-onset preeclampsia.
Description

EGTA- AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA- AM is also a Ca2+ chelator with slow chelating dynamics.
In Vitro

EGTA-AM (50 μM) markedly reduces the asynchronous excitatory postsynaptic currents (aEPSC) to 58.9 ± 8.1% of the control level, but only reduces the synchronous excitatory postsynaptic currents (EPSCs), measured as charge transfer produced by the stimulation train.
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

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Chemical Information

CAS Number

99590-86-0
Formula Weight

668.6
Molecular Formula

C26H40N2O18
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (149.57 mM; Ultrasonic (<60°C)
SMILES

CC(=O)OCOC(=O)CN(CCOCCOCCN(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Li MJ, et al. Cholinergic and glutamatergic transmission at synapses between pedunculopotine tegmental nucleus axonal terminals and A7 catecholamine cell group noradrenergic neurons in the rat. Neuropharmacology. 2016 Nov;110(Pt A):237-50?

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