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UNC 0646
CAS No. 1320288-17-2
UNC 0646( —— )
Catalog No. M22061 CAS No. 1320288-17-2
UNC 0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 84 | In Stock |
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| 5MG | 55 | In Stock |
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| 10MG | 98 | In Stock |
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| 25MG | 182 | In Stock |
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| 50MG | 318 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUNC 0646
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NoteResearch use only, not for human use.
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Brief DescriptionUNC 0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP).
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DescriptionUNC 0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646 potently blocks G9a/GLP methyltransferase activity in cells (IC50: 10 nM in MCF7 cells); exhibits low cellular toxicity (EC50: 4.7 μM in MCF7 cells).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorG9a| GLP
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Research Area——
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Indication——
Chemical Information
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CAS Number1320288-17-2
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Formula Weight621.9
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Molecular FormulaC36H59N7O2
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Purity>98% (HPLC)
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SolubilityDMSO:30 mg/mL (48.24 mM; Need ultrasonic)
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SMILESCOC1=C(OCCCN2CCCCC2)C=C2N=C(N=C(NC3CCN(CC3)C3CCCCC3)C2=C1)N1CCCN(CC1)C(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Liu F, et al. Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J Med Chem. 2011 Sep 8;54(17):6139-50.
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