AMP-PCP disodium

CAS No. 7414-56-4

AMP-PCP disodium( —— )

Catalog No. M33199 CAS No. 7414-56-4

AMP-PCP disodium, an ATP analogue, binds to the N-terminal domain of Hsp90 with a Kd value of 3.8 μM, facilitating the formation of an active Hsp90 homodimer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 140 In Stock
10MG 224 In Stock
25MG 377 In Stock
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Biological Information

  • Product Name
    AMP-PCP disodium
  • Note
    Research use only, not for human use.
  • Brief Description
    AMP-PCP disodium, an ATP analogue, binds to the N-terminal domain of Hsp90 with a Kd value of 3.8 μM, facilitating the formation of an active Hsp90 homodimer.
  • Description
    AMP-PCP disodium is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP disodium binding favors the formation of the active homodimer of Hsp90.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    HSP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    7414-56-4
  • Formula Weight
    549.17
  • Molecular Formula
    C11H16N5Na2O12P3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (182.09 mM; Ultrasonic)
  • SMILES
    O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(CP([O-])([O-])=O)(O)=O)(O)=O)N2C3=NC=NC(N)=C3N=C2.[Na+].[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhang H, et al. A dynamic view of ATP-coupled functioning cycle of Hsp90 N-terminal domain. Sci Rep. 2015 Apr 13;5:9542.?
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