HS-131

CAS No. ——

HS-131( HS131 )

Catalog No. M17005 CAS No. ——

HS-131 is an imaging probe of Hsp90 activity by linking it to a near-infrared (nIR) dye.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    HS-131
  • Note
    Research use only, not for human use.
  • Brief Description
    HS-131 is an imaging probe of Hsp90 activity by linking it to a near-infrared (nIR) dye.
  • Description
    HS-131 is an imaging probe of Hsp90 activity by linking it to a near-infrared (nIR) dye, HS131 uptake into cells correlated with cell membrane expression of Hsp90 and was used to image molecular subtypes of murine and human breast cancers in vitro and in murine models.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    HS131
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    HSP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    1318.697
  • Molecular Formula
    C71H95N7O13S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    4-(2-((1E,3Z)-3-(4-(21-((2-carbamoyl-5-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)-6,9,12,15,18-pentaoxa-2-azahenicosyl)phenyl)-5-((E)-3,3-dimethyl-1-(4-sulfobutyl)indolin-2-ylidene)penta-1,3-dien-1-yl)-3,3-dimethyl-3H-indol-1-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Osada T, et al. Clin Cancer Res. 2017 Dec 15;23(24):7531-7542.
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