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Abacavir hydroxyacetate
CAS No. 1446418-48-9
Abacavir hydroxyacetate( —— )
Catalog No. M33097 CAS No. 1446418-48-9
Abacavir hydroxyacetate is an orally active nucleoside analog reverse transcriptase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAbacavir hydroxyacetate
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NoteResearch use only, not for human use.
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Brief DescriptionAbacavir hydroxyacetate is an orally active nucleoside analog reverse transcriptase inhibitor.
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DescriptionAbacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems.
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In Vitro——
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In VivoAbacavir hydroxyacetate (10-20 mg/kg; p.o. once) effectively controls psoriasis of mice.Animal Model:6 to 8-week-old male and female SCID mice with implantation of psoriatic tissue Dosage:10 and 20 mg/kg Administration:Oral gavage; 10-20 mg/kg once Result:Decreased the concentration of PRINS and 1L-20, and reduced the lesion area of skin. Showed a better effect than methotrexate in controlling psoriasis.
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Synonyms——
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV Protease
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Research Area——
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Indication——
Chemical Information
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CAS Number1446418-48-9
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Formula Weight344.37
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Molecular FormulaC16H20N6O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 100 mg/mL (290.39 mM)
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SMILESNc1nc(NC2CC2)c2ncn([C@@H]3C[C@H](COC(=O)CO)C=C3)c2n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Bictegravir
Bictegravir (GS 9883) is a novel potent HIV-1 integrase (IN) that specifically targets IN strand transfer activity with IC50 of 7.5 nM.
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Helichrysetin
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.Searching for anti-HIV-1 protease (PR) inhibitors of Thai medicinal plants led to the isolation of a new cyclohexenyl chalcone named panduratin C and chalcone derivatives (2-6) from the methanol extract of Boesenbergia pandurata rhizomes.
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Terameprocol
Terameprocol is a synthetic tetra-methylated derivative of nordihydroguaiaretic acid (NDGA) and transcriptional inhibitor with potential antiviral, antiangiogenic, and antineoplastic activities. Terameprocol showed the strongest anti-HIV activity.
