Abacavir hydroxyacetate

Research use only, not for human use.

Abacavir hydroxyacetate is an orally active nucleoside analog reverse transcriptase inhibitor.

Abacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems.

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Abacavir hydroxyacetate (10-20 mg/kg; p.o. once) effectively controls psoriasis of mice.Animal Model:6 to 8-week-old male and female SCID mice with implantation of psoriatic tissue Dosage:10 and 20 mg/kg Administration:Oral gavage; 10-20 mg/kg once Result:Decreased the concentration of PRINS and 1L-20, and reduced the lesion area of skin. Showed a better effect than methotrexate in controlling psoriasis.

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Microbiology/Virology

HIV

HIV Protease

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1446418-48-9

344.37

C16H20N6O3

>98% (HPLC)

In Vitro:?DMSO : ≥ 100 mg/mL (290.39 mM)

Nc1nc(NC2CC2)c2ncn([C@@H]3C[C@H](COC(=O)CO)C=C3)c2n1

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(-20℃)

With Ice Pack

≥ 2 years