Orforglipron( —— )

Catalog No. M32937 CAS No. 2212020-52-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Orforglipron
Note

Research use only, not for human use.
Brief Description

Orforglipron (LY3502970; GLP-1 receptor agonist 1) is an orally available glucagon-like peptide (GLP-1) receptor agonist for the study of obesity and type 1 diabetes in adults.
Description

Orforglipron (LY3502970) (GLP-1 receptor agonist 1) is a GLP-1 receptor agonist extracted from patent WO2018056453A1, Compound 67.
In Vitro

Orforglipron is an incretin secreted from L cells of the small intestine when nutrients pass through the digestive tract, and glucose is transmitted via the GLP-1 receptor. Orforglipron exhibits various actions such as dependent gastric emptying delay, and feeding suppression.
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Glucagon Receptor
Recptor

Glucagon Receptor
Research Area

——
Indication

——

CAS Number

2212020-52-3
Formula Weight

882.96
Molecular Formula

C48H48F2N10O5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (113.26 mM; Ultrasonic (<60°C)
SMILES

[H][C@@]1(CCOC(C)(C)C1)c1ccc2n(c(cc2c1)C(=O)N1CCc2nn(c(c2[C@@H]1C)-n1ccn(-c2ccc3n(C)ncc3c2F)c1=O)-c1cc(C)c(F)c(C)c1)[C@]1(C[C@@H]1C)c1noc(=O)[nH]1
Chemical Name

——

1. Pyrazolopyridine derivative having glp-1 receptor agonist effect. WO2013046136A1.

Calculator

molnova catalog