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Home - Products - GPCR/G Protein - Glucagon Receptor - Tirzepatide

Tirzepatide

CAS No. 2023788-19-2

Tirzepatide( LY3298176 )

Catalog No. M29810 CAS No. 2023788-19-2

Tirzepatide (TZP), a novel dual GIP and GLP-1 receptor agonist (RA).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tirzepatide
  • Note
    Research use only, not for human use.
  • Brief Description
    Tirzepatide (TZP), a novel dual GIP and GLP-1 receptor agonist (RA).
  • Description
    Tirzepatide (TZP), a novel dual GIP and GLP-1 receptor agonist (RA).(In Vivo):Tirzepatide (LY3298176) shows significantly better efficacy with regard to glucose control and weight loss than do Dulaglutide.
  • In Vitro
    ——
  • In Vivo
    Tirzepatide (LY3298176) shows significantly better efficacy with regard to glucose control and weight loss than do Dulaglutide.
  • Synonyms
    LY3298176
  • Pathway
    GPCR/G Protein
  • Target
    Glucagon Receptor
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2023788-19-2
  • Formula Weight
    4813.45
  • Molecular Formula
    C225H348N48O68
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (10.39 mM)
  • SMILES
    ——
  • Chemical Name
    Sequence:Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-Ile-Ala-Gln-{diacid-gamma-Glu-(AEEA)2-Lys}-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Frias JP, et al. Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial. Lancet. 2018 Nov 17;392(10160):2180-2193.
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