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BI-1408
CAS No. 2231075-94-6
BI-1408( —— )
Catalog No. M32808 CAS No. 2231075-94-6
BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 532 | Get Quote |
|
| 5MG | 787 | Get Quote |
|
| 10MG | 1074 | Get Quote |
|
| 25MG | 1463 | Get Quote |
|
| 50MG | 1822 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBI-1408
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NoteResearch use only, not for human use.
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Brief DescriptionBI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).
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DescriptionBI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayNeuroscience
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TargetGamma-secretase
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RecptorGamma-secretase
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Research Area——
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Indication——
Chemical Information
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CAS Number2231075-94-6
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Formula Weight390.46
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Molecular FormulaC22H23FN6
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Purity>98% (HPLC)
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Solubility——
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SMILESN(C=1N=C2C(=CC=CN2N1)C3=C(C)C=C(F)C=C3)[C@H]4CC5=C(CC4)N(CC)N=C5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gerlach K, et al. Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators. Bioorg Med Chem. 2018 Jul 23;26(12):3227-3241.?
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