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Aβ42-IN-2

CAS No. 1914989-80-2

Aβ42-IN-2( —— )

Catalog No. M37643 CAS No. 1914989-80-2

Aβ42-IN-2, a γ-secretase modulator with an IC50 of 6.5 nM for Αβ42, can be used for Alzheimer's disease research .

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	89	In Stock
5MG	82	In Stock
10MG	129	In Stock
25MG	215	In Stock
50MG	299	In Stock
100MG	412	In Stock
200MG	570	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Aβ42-IN-2
Note

Research use only, not for human use.
Brief Description

Aβ42-IN-2, a γ-secretase modulator with an IC50 of 6.5 nM for Αβ42, can be used for Alzheimer's disease research .
Description

Aβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 has an IC50 of 6.5 nM for Αβ42.Aβ42-IN-2 can be used for the research of Alzheimer's disease.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Neuroscience
Target

Gamma-secretase
Recptor

Gamma-secretase
Research Area

——
Indication

——

Chemical Information

CAS Number

1914989-80-2
Formula Weight

430.5
Molecular Formula

C24H26N6O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 20 mg/mL (46.46 mM; Ultrasonic )
SMILES

COc1ccc(cc1)[C@H](C)Nc1nnc(cc1C)-c1ccc(c(OC)n1)-n1cnc(C)c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Steven L. Wagner, et al. Potent gamma-secretase modulators. WO2016070107A1.

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