Isourolithin A is a naturally occurring compound found in a variety of plants, including parsley, celery and chamomile.

3'-Hydroxy-4'-methoxyacetophenone is an active P. spinosa extract. It possesses anti-inflammatory activity and prevented injuries due to administration of acetic acid in the colon.

Z16078526 enhances thermogenesis in mice by inducing endogenous Ucp1 expression, promoting p38 MAPK phosphorylation, and stimulating lipolysis in primary mouse brown adipocytes.