Columbianetin may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of columbianetin acetate is a passive diffusion process without pH-dependent.

EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM.

Perhexiline is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2).