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D3-βArr
CAS No. 662164-09-2
D3-βArr( NCGC00379308 )
Catalog No. M20139 CAS No. 662164-09-2
D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR) which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 33 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 49 | In Stock |
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| 25MG | 107 | In Stock |
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| 50MG | 183 | In Stock |
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| 100MG | 272 | In Stock |
|
| 200MG | 405 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameD3-βArr
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NoteResearch use only, not for human use.
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Brief DescriptionD3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR) which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
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DescriptionD3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR) which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
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In Vitro——
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In Vivo——
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SynonymsNCGC00379308
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PathwayOthers
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TargetOther Targets
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Recptorthyrotropin receptor (TSHR)
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Research Area——
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Indication——
Chemical Information
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CAS Number662164-09-2
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Formula Weight333.43
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Molecular FormulaC20H23N5
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Purity>98% (HPLC)
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SolubilityDMSO: 100 mg/mL (299.91 mM)
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SMILESCC(Nc1nc(nc2ccccc12)N1CCNCC1)c1ccccc1
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Chemical NameN-(1-Phenylethyl)-2-(1-piperazinyl)-4-quinazolinamine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Neumann S et al. Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro. J Pharmacol Exp Ther. 2018 Jan;364(1):38-45.
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