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GSK-25

CAS No. 874119-56-9

GSK-25( —— )

Catalog No. M17637 CAS No. 874119-56-9

GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 91 In Stock
2MG 51 In Stock
5MG 80 In Stock
10MG 113 In Stock
25MG 171 In Stock
50MG 266 In Stock
100MG 445 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    GSK-25
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
  • Description
    GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    RSK1| mTOR (p70S6K)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    874119-56-9
  • Formula Weight
    513.34
  • Molecular Formula
    C24H16Cl2F2N6O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (97.40 mM)
  • SMILES
    Clc1nccc(c1)C=2NC(C)=C(C(N=2)c3ccc(Cl)cc3F)C(=O)Nc4cc5cnnc5cc4F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sehon CA, et al. J Med Chem. 2008 Nov 13;51(21):6631-4.
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