Derrone

Research use only, not for human use.

Derrone may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens.

Derrone may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens. It is also a novel Aurora kinase inhibitor, it can significantly inhibit the formation and growth of MCF7 tumor spheroids.

Derrone (30-60 μM, 15 days) significantly inhibits the formation and growth of MCF7 tumor spheroids, with the tumor spheroid growth inhibition (% TGI) of 17.5% and 65.4% for 30 and 60?μM Derrone, respectively. Derrone shows the autophagic features, such as the conversion of LC3-I to LC3-II, the formation of autophagosome and the downregulation of SQSTM1/p62 (p62).Derrone induces autophagic cell death through intracellular ROS and sustained ERK phosphorylation in A549 cells.

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Others

Other Targets

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76166-59-1

336.34

C20H16O5

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years