Cart
sales@molnova.com
RGD peptide GRGDNP
CAS No. 114681-65-1
RGD peptide GRGDNP( —— )
Catalog No. M30440 CAS No. 114681-65-1
RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 41 | In Stock |
|
| 5MG | 68 | In Stock |
|
| 10MG | 111 | In Stock |
|
| 25MG | 227 | In Stock |
|
| 50MG | 330 | In Stock |
|
| 100MG | 490 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameRGD peptide GRGDNP
-
NoteResearch use only, not for human use.
-
Brief DescriptionRGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering.
-
DescriptionRGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering.
-
In VitroRGD peptide (GRGDNP) (50 μM ; preincubation for 3 hours before stretch) abolishes stretch-induced IKK activation and IL-6 mRNA expression. It shows little effect on the IKK activity and IL-6 mRNA expression in unstretched HUVECs. RGD peptide (GRGDNP) (300?μg/mL; for 6?hours) completely reverses enhanced FN1 expression in oxygen glucose deprivation(OGD) treated primary hippocampal neurons, HT22 cell lines and in its sEVs.
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetIntegrin
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number114681-65-1
-
Formula Weight614.61
-
Molecular FormulaC23H38N10O10
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 3.12 mg/mL (5.08 mM)
-
SMILES——
-
Chemical NameSequence:{Gly}{Arg}{Gly}{Asp}{Asn}{Pro}
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
Ruoslahti, E., and ?brink, B. Common principles in cell adhesion Experimental Cell Research 227, 1-11 (1996).
molnova catalog
related products
-
Gantofiban
Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.
-
SC-68448
SC-68448 (SC68448) is a potent, selective peptidomimetic antagonist of the integrin αvβ3 with IC50 of 1 nM.
-
Gly-Arg-Gly-Asp-Ser
Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.
