RGD peptide GRGDNP

CAS No. 114681-65-1

RGD peptide GRGDNP( —— )

Catalog No. M30440 CAS No. 114681-65-1

RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 41 In Stock
5MG 68 In Stock
10MG 111 In Stock
25MG 227 In Stock
50MG 330 In Stock
100MG 490 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    RGD peptide GRGDNP
  • Note
    Research use only, not for human use.
  • Brief Description
    RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering.
  • Description
    RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering.
  • In Vitro
    RGD peptide (GRGDNP) (50 μM ; preincubation for 3 hours before stretch) abolishes stretch-induced IKK activation and IL-6 mRNA expression. It shows little effect on the IKK activity and IL-6 mRNA expression in unstretched HUVECs. RGD peptide (GRGDNP) (300?μg/mL; for 6?hours) completely reverses enhanced FN1 expression in oxygen glucose deprivation(OGD) treated primary hippocampal neurons, HT22 cell lines and in its sEVs.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Integrin
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    114681-65-1
  • Formula Weight
    614.61
  • Molecular Formula
    C23H38N10O10
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 3.12 mg/mL (5.08 mM)
  • SMILES
    ——
  • Chemical Name
    Sequence:{Gly}{Arg}{Gly}{Asp}{Asn}{Pro}

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Ruoslahti, E., and ?brink, B. Common principles in cell adhesion Experimental Cell Research 227, 1-11 (1996).
molnova catalog
related products
  • Lifitegrast sodium

    Lifitegrast sodium (SAR-1118-023 sodium) is a small molecule integrin antagonist that inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), which reduces inflammation of the ocular surface, and may be used in the study of dry eye.

  • Tirofiban hydrochlor...

    A potent, selective inhibitor of the platelet fibrinogen receptor GPIIb/IIIa with IC50 of 9 nM.

  • BMS-688521

    BMS-688521 BMS-688521 is an orally active and potent inhibitor of LFA-1/ICAM interaction, a small molecule antagonist of leukocyte function-associated antigen-1 (LFA-1), with potential anti-inflammatory activity.