Difopein TFA (396834-58-5 free base)( —— )

Catalog No. M30250 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Difopein TFA (396834-58-5 free base)
Note

Research use only, not for human use.
Brief Description

Difopein (TFA), a specific and competitive inhibitor of 14-3-3 protein (a highly conserved eukaryotic regulatory molecule), blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interactions. Difopein (TFA) leads to induction of apoptosis and enhances the ability of cisplatin to kill cells.
Description

Difopein (TFA), a specific and competitive inhibitor of 14-3-3 protein (a highly conserved eukaryotic regulatory molecule), blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interactions. Difopein (TFA) leads to induction of apoptosis and enhances the ability of cisplatin to kill cells.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

14-3-3 protein
Research Area

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Indication

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CAS Number

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Formula Weight

6501.19
Molecular Formula

C275H425N76F3O91S6
Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

Sequence:{Ser}{Ala}{Asp}{Gly}{Ala}{Pro}{His}{Cys}{Val}{Pro}{Arg}{Asp}{Leu}{Ser}{Trp}{Leu}{Asp}{Leu}{Glu}{Ala}{Asn}{Met}{Cys}{Leu}{Pro}{Gly}{Ala}{Ala}{Gly}{Leu}{Asp}{Ser}{Ala}{Asp}{Gly}{Ala}{Pro}{His}{Cys}{Val}{Pro}{Arg}{Asp}{Leu}{Ser}{Trp}{Leu}{Asp}{Leu}{Glu}{Ala}{Asn}{Met}{Cys}{Leu}{Pro}{Gly}{Ala}{Ala}{Gly}{Leu}{Glu}