HAEGTFTSDVS

Research use only, not for human use.

HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.

HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.(In Vitro):The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists.

The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists.

——

——

GPCR/G Protein

Glucagon Receptor

——

——

——

864915-61-7

1150.18

C48H71N13O20

>98% (HPLC)

——

——

Sequence:His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser

(-20℃)

With Ice Pack

≥ 2 years