N-Caffeoyltryptophan

CAS No. 109163-69-1

N-Caffeoyltryptophan( trans-Caffeoyl-L-tryptophan )

Catalog No. M29476 CAS No. 109163-69-1

N-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 246 In Stock
2MG 141 In Stock
5MG 227 In Stock
10MG 337 In Stock
25MG 559 In Stock
50MG 779 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    N-Caffeoyltryptophan
  • Note
    Research use only, not for human use.
  • Brief Description
    N-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).
  • Description
    N-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).(In Vitro):In cellular levels,N-Caffeoyltryptophan was able to increase the acetylation of total lysine, cortactin and histone H3 in neuronal NG108-15 cells. In the same cells, the amide also increased the acetylation of lysine (K382) in p53, but not (K305).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    trans-Caffeoyl-L-tryptophan
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    Sirtuin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    109163-69-1
  • Formula Weight
    366.373
  • Molecular Formula
    C20H18N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)\C=C\c1ccc(O)c(O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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