(-)-Denudatin B

Research use only, not for human use.

(-)-Denudatin B is derived from Magnolia fargesii. (-)-Denudatin B has nonspecific antiplatelet action at high concentration by inhibiting phosphoinositides breakdown induced by collagen and thrombin.

(-)-Denudatin B is derived from Magnolia fargesii. (-)-Denudatin B has nonspecific antiplatelet action at high concentration by inhibiting phosphoinositides breakdown induced by collagen and thrombin.(In Vitro):Denudatin B inhibits the aggregation and ATP release of washed rabbit platelets caused by platelet-activating factor (PAF) in a concentration-dependent manner. High concentration of Denudatin B (greater than 50 micrograms/ml) inhibits the aggregation and ATP release of platelets caused by ADP, collagen, arachidonic acid and thrombin. Denudatin B suppresses thrombin-induced rise of the intracellular calcium concentration.

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Denudatin B

Endocrinology/Hormones

ATPase

ATPase

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87402-88-8

356.41

C21H24O5

>98% (HPLC)

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O(C)[C@@]12C(O[C@@]([C@H]1C)(C3=CC(OC)=C(OC)C=C3)[H])=CC(=O)C(CC=C)=C2

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(-20℃)

With Ice Pack

≥ 2 years