Home - Products - Membrane Transporter/Ion Channel - TRP/TRPV Channel - NGD-8243

NGD-8243

CAS No. 573678-04-3

NGD-8243( N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine | NGD8243 | NGD 8243 )

Catalog No. M28921 CAS No. 573678-04-3

NGD-8243 is a TRPV1 inhibitor and can be used in studies for prevention and treatment of cardiac hypertrophy.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	472	In Stock
5MG	415	In Stock
10MG	614	In Stock
25MG	938	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

NGD-8243
Note

Research use only, not for human use.
Brief Description

NGD-8243 is a TRPV1 inhibitor and can be used in studies for prevention and treatment of cardiac hypertrophy.
Description

NGD-8243 is a TRPV1 inhibitor and can be used in studies for prevention and treatment of cardiac hypertrophy.
In Vitro

——
In Vivo

——
Synonyms

N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine | NGD8243 | NGD 8243
Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

573678-04-3
Formula Weight

434.345
Molecular Formula

C21H12F6N4
Purity

>98% (HPLC)
Solubility

——
SMILES

FC(F)(F)c1ccc(Nc2ncnc3cc(ccc23)-c2ncccc2C(F)(F)F)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Xue Z, Yan R, Yang B. Phenylethanoid glycosides and phenolic glycosides from stem bark of Magnolia officinalis. Phytochemistry. 2016 Jul;127:50-62.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

JNJ-17203212

A potent, selective and orally bioavailable TRPV1 receptor antagonist with IC50 of 65 nM and 102 nM for hTRPV1 and rTRPV1, respectively.
HhAntag

HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway with the anti-tumor activity.
RN-1747

RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: hTRPV4 of 0.77 μM, mTRPV4 of 4.0 μM, and rTRPV4 of 4.1 μM). RN-1747 also antagonizes TRPM8 (IC50: 4 μM).

Sign In Join Free