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Home - Products - Metabolic Enzyme/Protease - P450 - 1-Ethynylpyrene

1-Ethynylpyrene

CAS No. 34993-56-1

1-Ethynylpyrene( —— )

Catalog No. M28844 CAS No. 34993-56-1

1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    1-Ethynylpyrene
  • Note
    Research use only, not for human use.
  • Brief Description
    1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).
  • Description
    1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).(In Vitro):The Ki values of 1-Ethynylpyrene against P450 1A2, and 2B1 is 0.32 and 0.04 μM, respectively.
  • In Vitro
    1-Ethynylpyrene exhibits activity against P450 1A2, and 2B1 with Kis of 0.32 and 0.04 μM, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    LFA-1|ICAM-1|IL-2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    34993-56-1
  • Formula Weight
    226.278
  • Molecular Formula
    C18H10
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 9.09 mg/mL (40.17 mM)
  • SMILES
    C#Cc1ccc2ccc3cccc4ccc1c2c34
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tazawa K, Koutsogiannaki S, Chamberlain M, Yuki K. The effect of different anesthetics on tumor cytotoxicity by natural killer cells. Toxicol Lett. 2017 Jan 15;266:23-31.
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