Dafadine-A

CAS No. 1065506-69-5

Dafadine-A( —— )

Catalog No. M23270 CAS No. 1065506-69-5

Dafadine-A is an analog of dafadine and a novel inhibitor of DAF-9 cytochrome P450 in the nematode Caenorhabditis elegans.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 42 In Stock
5MG 38 In Stock
10MG 53 In Stock
25MG 112 In Stock
50MG 198 In Stock
100MG 296 In Stock
200MG Get Quote In Stock
500MG 706 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Dafadine-A
  • Note
    Research use only, not for human use.
  • Brief Description
    Dafadine-A is an analog of dafadine and a novel inhibitor of DAF-9 cytochrome P450 in the nematode Caenorhabditis elegans.
  • Description
    Dafadine-A is an analog of dafadine and a novel inhibitor of DAF-9 cytochrome P450 in the nematode Caenorhabditis elegans. Mammalian orthologs that also inhibit DAF-9 (CYP27A1).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    P450
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1065506-69-5
  • Formula Weight
    391.46
  • Molecular Formula
    C23H25N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (127.73 mM; Need ultrasonic)
  • SMILES
    CC1=C(C(=CC=C1)C)OCC2=CC(=NO2)C(=O)N3CCC(CC3)C4=CC=NC=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Luciani GM, et al. Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans. Nat Chem Biol. 2011 Nov 6;7(12):891-3.
molnova catalog
related products
  • Tienilic Acid

    Tienilic Acid is a uricosuric diuretic with certain hepatotoxicity.

  • N-Nornuciferine hydr...

    N-Nornuciferine is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).N-Nornuciferine strongly inhibits CYP2D6 activity but shows weak or no inhibition of the other four P450 isoenzymes (CYP2C19, CYP3A4, CYP2E1, CYP2C9). N-Nornuciferine competitively inhibits the CYP2D6-catalyzed dextromethorphan O-demethylation (Ki: 2.34 μM).

  • N-Desethyl Chloroqui...

    N-Desethyl Chloroquine Hydrochloride ((±)-Desethylchloroquine 2HCl) is a desethylchloroquine derivative. desethylchloroquine competitively inhibits cyp2d1 /6-mediated reactions in vitro and in vivo.