KCNQ2/3 activator-1
CAS No. 1009344-33-5
KCNQ2/3 activator-1( N-[4-(6-Fluoro-3,4-dihydro-2(1H)-isoquinolinyl)-2,6-dimethylphenyl]-3,3-dimethylbutanamide )
Catalog No. M28661 CAS No. 1009344-33-5
N-[4-(6-Fluoro-3,4-dihydro-2(1H)-isoquinolinyl)-2,6-dimethylphenyl]-3,3-dimethylbutanamide is a chemical compound.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 59 | In Stock |
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| 2MG | 32 | In Stock |
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| 5MG | 53 | In Stock |
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| 10MG | 82 | In Stock |
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| 25MG | 147 | In Stock |
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| 50MG | 231 | In Stock |
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| 100MG | 365 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 918 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameKCNQ2/3 activator-1
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NoteResearch use only, not for human use.
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Brief DescriptionN-[4-(6-Fluoro-3,4-dihydro-2(1H)-isoquinolinyl)-2,6-dimethylphenyl]-3,3-dimethylbutanamide is a chemical compound.
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DescriptionN-[4-(6-Fluoro-3,4-dihydro-2(1H)-isoquinolinyl)-2,6-dimethylphenyl]-3,3-dimethylbutanamide is a chemical compound.
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In Vitro——
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In Vivo——
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SynonymsN-[4-(6-Fluoro-3,4-dihydro-2(1H)-isoquinolinyl)-2,6-dimethylphenyl]-3,3-dimethylbutanamide
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PathwayOthers
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TargetOther Targets
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RecptorD3
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Research Area——
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Indication——
Chemical Information
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CAS Number1009344-33-5
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Formula Weight368.49
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Molecular FormulaC23H29FN2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (135.69 mM)
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SMILESCC(C)(C)CC(Nc(c(C)c1)c(C)cc1N(CC1)Cc(cc2)c1cc2F)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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ISRIB-A15
ISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.
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CALP1
Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-1 gp120-activated channels, inhibiting Ca2+-mediated cytotoxicity and apoptosis (IC50 = 52 μM). Shown to protect pancreatic acinar cells from gossypol induced necrosis. Inhibits VLA-5-mediated adhesion of mast cells to fibronectin in vitro and attenuates inflammatory cell influx in guinea pig lung in vivo.
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3,5-Dihydroxy-4,6,7-...
Eupatorin analog. Reference standards.
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