SJ572403( SJ403 )

Catalog No. M26819 CAS No. 19970-45-7

SJ572403 is an inhibitor of disordered protein p27.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	87	In Stock
5MG	79	In Stock
10MG	122	In Stock
25MG	244	In Stock
50MG	384	In Stock
100MG	555	In Stock
200MG	733	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

SJ572403
Note

Research use only, not for human use.
Brief Description

SJ572403 is an inhibitor of disordered protein p27.
Description

SJ572403 is an inhibitor of disordered protein p27.(In Vitro):SJ572403 (10 μM-3 mM) replaces p27-D2 on Cdk2/cyclin A and partially restores Cdk2 kinase activity. SJ572403 (0-3 mM) modulates Cdk regulation of p27.
In Vitro

SJ572403 (SJ403) (3 mM) shows specific interactions with specific regions within the D2 subdomain of p27-KID with a Kd value of 2.2 mM.SJ572403 (0-3 mM) modulates p27's Cdk regulatory.SJ572403 (10 μM-3 mM) displaces p27-D2 from Cdk2/cyclin A and partially restores Cdk2 kinase activity.
In Vivo

——
Synonyms

SJ403
Pathway

Others
Target

Other Targets
Recptor

HIV-1
Research Area

——
Indication

——

Chemical Information

CAS Number

19970-45-7
Formula Weight

275.312
Molecular Formula

C13H17N5O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 13.89 mg/mL (50.45 mM)
SMILES

CCn1c(C)c(C)n2c1nc1n(C)c(=O)n(C)c(=O)c21
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Kortagere S, et al. Structure-activity relationships of a novel capsid targeted inhibitor of HIV-1 replication. J Chem Inf Model. 2014 Nov 24;54(11):3080-90.

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