Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Calcium Channel - N-Desalkylflurazepam

N-Desalkylflurazepam

CAS No. 2886-65-9

N-Desalkylflurazepam( Norfludiazepam )

Catalog No. M28291 CAS No. 2886-65-9

N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepine compounds, such as Flurazepam. N-Desalkylflurazepam inhibits L-type voltage-gated calcium channels with IC 50 values of 55 μM and 37 μM for Ca v 1.2 and Ca v 1.3 , respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 49 Get Quote
25MG 89 Get Quote
50MG 147 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    N-Desalkylflurazepam
  • Note
    Research use only, not for human use.
  • Brief Description
    N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepine compounds, such as Flurazepam. N-Desalkylflurazepam inhibits L-type voltage-gated calcium channels with IC 50 values of 55 μM and 37 μM for Ca v 1.2 and Ca v 1.3 , respectively.
  • Description
    N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepine compounds, such as Flurazepam. N-Desalkylflurazepam inhibits L-type voltage-gated calcium channels with IC 50 values of 55 μM and 37 μM for Ca v 1.2 and Ca v 1.3 , respectively.(In Vitro):Flurazepam's long-acting metabolite, N-Desalkylflurazepam, reduces the amplitudes of all the evoked potentials (EPs) components .
  • In Vitro
    Flurazepam's long-acting metabolite, N-Desalkylflurazepam, reduces the amplitudes of all the evoked potentials (EPs) components.
  • In Vivo
    ——
  • Synonyms
    Norfludiazepam
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    S-adenosylmethionine decarboxylase (SAMDC)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2886-65-9
  • Formula Weight
    288.71
  • Molecular Formula
    C15H10ClFN2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (346.38 mM)
  • SMILES
    Fc1ccccc1C1=NCC(=O)Nc2ccc(Cl)cc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kramer DL, et al. Lysosomal sequestration of polyamine analogues in Chinese hamster ovary cells resistant to the S-adenosylmethionine decarboxylase inhibitor, CGP-48664. Cancer Res. 1998 Sep 1;58(17):3883-90.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Flosatidil

    Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases, and can be used in the study of angina pectoris.

  • GSK-7975A

    A selective CRAC channel blocker that inhibits store-operated Ca(2+) entry with IC50 of 3.4 uM.

  • Azumolene

    Azumolene1.EU4093 (azumolene sodium) is a direct acting, skeletal muscle relaxant with structural similarities to dantrolene sodium in that the para-nitro phenyl group of dantrolene sodium is replaced by a para-bromo phenyl group.?2.?The effect of EU4093 on the twitch of the intact rat soleus preparation is nearly maximal at a dose of 20 mg kg-1.?

Sign In Join Free