BML-259

CAS No. 267654-00-2

BML-259( CAY10554 )

Catalog No. M28107 CAS No. 267654-00-2

BML-259 is an inhibitor of CDK5 and CDK2 with IC50s of 64 and 98 nM, respectively. BML-259 can be used in studies about the treatment of cancer and neurodegenerative diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 46 In Stock
5MG 41 In Stock
10MG 73 In Stock
25MG 163 In Stock
50MG 272 In Stock
100MG 477 In Stock
200MG Get Quote In Stock
500MG 1014 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BML-259
  • Note
    Research use only, not for human use.
  • Brief Description
    BML-259 is an inhibitor of CDK5 and CDK2 with IC50s of 64 and 98 nM, respectively. BML-259 can be used in studies about the treatment of cancer and neurodegenerative diseases.
  • Description
    BML-259 is an inhibitor of CDK5 and CDK2 with IC50s of 64 and 98 nM, respectively. BML-259 can be used in studies about the treatment of cancer and neurodegenerative diseases.(In Vitro):BML-259 prevents a large population of cells from NAC-evoked cell death.
  • In Vitro
    BML-259 (10 μM) protects large population of cells against non-Aβ component of Alzheimer's disease amyloid (NAC)-evoked cell death.
  • In Vivo
    ——
  • Synonyms
    CAY10554
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    Antifungal|Antiviral
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    267654-00-2
  • Formula Weight
    260.36
  • Molecular Formula
    C14H16N2OS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (480.12 mM)
  • SMILES
    O=C(NC1=NC=C(S1)C(C)C)CC=2C=CC=CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Freitas-Silva O, et al. Tracing fungi secondary metabolites in Brazil nuts using LC-MS/MS. Drug Metab Lett. 2011 Aug;5(3):150-5.
molnova catalog
related products
  • ISOPIMPINELLIN

    Antiviral, anti HIV.

  • Indirubin-3-monoxime

    Indirubin-3-monoxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.

  • JNJ-7706621

    A dual CDK/Aurora kinase inhibitor with IC50 of 9/4/11/15 nM for CDK1/CDK2/Aurora A/Aurora B respectively; also exhibits activity towards CDK3, CDK4, and CDK6 (IC50s=50-250 nM).