ISOPIMPINELLIN

Research use only, not for human use.

Antiviral, anti HIV.

Antiviral, anti HIV.

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Isopimpinellin (oral gavage, 35-150 mg/kg) inhibits B[a]P-DNA adduct formation and DMBA–DNA adduct formation in SENCAR mice with skin tumor. Animal Model:Female SENCAR mice (7-9 weeks of age) were fed AIN-76A semi-purified diet (Dyets, Bethlehem, PA) for 2 weeks prior to and during the study.Dosage:35–150 mg/kg.Administration:Oral gavage, suspended in 0.1 mL corn oil at 24 h and 2 h prior to topical treatment with [3H]B[a]P (200 nmol, 1 Ci/mmol) or [3H]DMBA (10 nmol, 10 Ci/mmol) (each in 0.2 mL acetone).Result:Significantly inhibited B[a]P-DNA adduct formation by 37 and 26%, respectively.Isopimpinellin (35, 70 and 150 mg/kg) blocked DMBA–DNA adduct formation by 23, 56 and 69%, respectively

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Angiogenesis

CDK

Antiviral

Cancer

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482-27-9

246.22

C13H10O5

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (203.07 mM)

COc1c2ccoc2c(OC)c2oc(=O)ccc12

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(-20℃)

With Ice Pack

≥ 2 years