Cart
sales@molnova.com
Diloxanide
CAS No. 579-38-4
Diloxanide( RD 3803 | RD-3803 | RD3803 | Diloxanide | Diloxanid | Diloxanida )
Catalog No. M27976 CAS No. 579-38-4
Diloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 54 | Get Quote |
|
| 50MG | 77 | Get Quote |
|
| 100MG | 128 | Get Quote |
|
| 200MG | 192 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameDiloxanide
-
NoteResearch use only, not for human use.
-
Brief DescriptionDiloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.
-
DescriptionDiloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.
-
In Vitro——
-
In VivoDiloxanide is hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate.Diloxanide furoate (oral administraion; 75-200 mg/kg; 3 days; once daily) is effective at different dose of dayin weanling rats. At 200 mg/kg, 100% of the treated rats are cured and no amoebic lesions are observed in the caecum. Besides, 85%,77%, and 44.4% of the treated rats are cured at the dose 150 mg/kg, 100 mg/kg, and 75 mg/kg, respectively. The ED50 value is 77.9 mg/kg for this agent in rats.
-
SynonymsRD 3803 | RD-3803 | RD3803 | Diloxanide | Diloxanid | Diloxanida
-
PathwayMicrobiology/Virology
-
TargetParasite
-
RecptorTNNI3 Interacting Kinase (TNNI3K)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number579-38-4
-
Formula Weight234.08
-
Molecular FormulaC9H9Cl2NO2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 33.33 mg/mL (142.39 mM)
-
SMILESCN(C(=O)C(Cl)Cl)c1ccc(O)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Patterson JR, et, al. Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf. J Med Chem. 2021 Nov 11;64(21):15651-15670.
molnova catalog
related products
-
Pafuramidine
Pafuramidine (DB289) is an experimental prodrug of the orally active metabolite DB75, a potent antiparasitic compound with anti-malarial activity used in the study of parasitic infections and sleeping sickness.
-
AQ-13 dihydrochlorid...
AQ-13 dihydrochloride is an antimalarial drug. It is effective against drug-resistant strains of Plasmodium falciparum.
-
2-Hydroxy-3,4-dimeth...
2'-Hydroxy-3,4-dimethoxychalcone, a chalcone compound isolated from the roots of Sophora japonica, has antioxidant activity and inhibited the intracellular survival of Lactobacillus donovani Parasite EC.50 Values ranged between 0.39 and 0.41 μg/mL, which can be used in the study of diabetes, treatment of schistosomiasis, malaria and other infections.
