Ursodeoxycholic acid sodium

Research use only, not for human use.

Ursodeoxycholic acid sodium is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors,

Ursodeoxycholic acid sodium is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors,

——

Ursodeoxycholic acid (50, 150, and 450 mg/kg; p.o.; daily for 21 days) sodium results in weight loss in C57BL/6J wildtype mice. Animal Model:5 week old C57BL/6J WT mice (male and female)Dosage:50, 150, and 450 mg/kg dissolved in corn oilAdministration:Oral gavage; daily for 21 days Result:Mice in the 50 and 450 mg/kg groups sustained significant weight loss within a week. At 50 mg/kg, this weight loss persisted over the course of the experiment. At 450 mg/kg, initially weight loss was noted during the first and third week of ursodiol administration. At 150 mg/kg, it did not have significantly different weights compared to the untreated mice.

Ursodeoxycholate sodium | UDCA sodium | UDCA Na | Sodium Ursodeoxycholate | Ursodeoxycholic Acid (sodium salt)

Metabolic Enzyme/Protease

FXR

Bacterial

——

——

2898-95-5

414.562

C24H39NaO4

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (301.53 mM)

[H][C@@]12CC[C@H]([C@H](C)CCC(=O)O[Na])[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@@H](O)C[C@]2([H])C[C@H](O)CC[C@]12C

——

(-20℃)

With Ice Pack

≥ 2 years