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GSK-2324
CAS No. 1020567-30-9
GSK-2324( GSK2324 | GSK 2324 )
Catalog No. M10099 CAS No. 1020567-30-9
GSK-2324 (GSK2324) is a potent, selective, full FXR agonist with EC50 of 120 nM in FRET assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 787 | In Stock |
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| 10MG | 1074 | In Stock |
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| 25MG | 1596 | In Stock |
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| 50MG | 2130 | In Stock |
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| 100MG | 2762 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameGSK-2324
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NoteResearch use only, not for human use.
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Brief DescriptionGSK-2324 (GSK2324) is a potent, selective, full FXR agonist with EC50 of 120 nM in FRET assay.
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DescriptionGSK-2324 (GSK2324) is a potent, selective, full FXR agonist with EC50 of 120 nM in FRET assay; lowers body weight gain and serum glucose in a DIO mouse model of diabetes.
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In Vitro——
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In Vivo——
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SynonymsGSK2324 | GSK 2324
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PathwayMetabolic Enzyme/Protease
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TargetFXR
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RecptorFXR
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Research Area——
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Indication——
Chemical Information
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CAS Number1020567-30-9
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Formula Weight533.405
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Molecular FormulaC29H22Cl2N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC=C(C=C3)C4=CC5=C(C=C4)N=C(C=C5)C(=O)O
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Chemical Name6-(4-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)phenyl)quinoline-2-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bass JY, et al. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1206-13.
2. de Aguiar Vallim TQ, et al. Circ Res. 2013 Jun 7;112(12):1602-12.
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