Cart
sales@molnova.com
MFA-1
CAS No. 139755-30-9
MFA-1( Merck FXR agonist 1 )
Catalog No. M11658 CAS No. 139755-30-9
MFA-1 (Merck FXR agonist 1) is a potent, synthetic FXR agonist with EC50 of 16.9 nM in coactivator recruitment assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameMFA-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionMFA-1 (Merck FXR agonist 1) is a potent, synthetic FXR agonist with EC50 of 16.9 nM in coactivator recruitment assays.
-
DescriptionMFA-1 (Merck FXR agonist 1) is a potent, synthetic FXR agonist with EC50 of 16.9 nM in coactivator recruitment assays, displays 500-fold more potent than CDCA; displays an unexpected mode of binding and activation to FXR.
-
In Vitro——
-
In Vivo——
-
SynonymsMerck FXR agonist 1
-
PathwayMetabolic Enzyme/Protease
-
TargetFXR
-
RecptorFXR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number139755-30-9
-
Formula Weight420.549
-
Molecular FormulaC27H32O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name17beta-(4-hydroxybenzoyl)androsta-3,5-diene-3-carboxylic acid
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Soisson SM, et al. Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5337-42.
molnova catalog
related products
-
GW-4064
A potent and selective FXR agonist with EC50 of 15 nM in cell-free assay.
-
Tauro-Obeticholic ac...
Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).
-
Gly-β-MCA
Gly-β-MCA is an orally bioactive, enteroselective and potent inhibitor of the farnesoid X receptor (FXR), a bile acid, used in the study of obesity and diabetes.
