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Mesendogen
CAS No. 864716-85-8
Mesendogen( —— )
Catalog No. M27900 CAS No. 864716-85-8
Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7 magnesium channel activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 90 | In Stock |
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| 5MG | 80 | In Stock |
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| 10MG | 140 | In Stock |
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| 25MG | 306 | In Stock |
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| 50MG | 524 | In Stock |
|
| 100MG | 737 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMesendogen
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NoteResearch use only, not for human use.
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Brief DescriptionMesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7 magnesium channel activity.
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DescriptionMesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7 magnesium channel activity.
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In VitroWestern Blot Analysis Cell Line:H9 hESCs Concentration:10 μM Incubation Time:7 days Result:Downregulated expression levels of pluripotency markers OCT4 and SOX2.
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetTRP/TRPV Channel
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Recptor5-HT1B
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Research Area——
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Indication——
Chemical Information
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CAS Number864716-85-8
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Formula Weight400.84
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Molecular FormulaC18H16ClF3N2OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (249.47 mM)
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SMILESCC(C)c1ccc(cc1)C(=O)NC(=S)Nc1cc(ccc1Cl)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Knobelman DA, Kung HF, Lucki I. Regulation of extracellular concentrations of 5-hydroxytryptamine (5-HT) in mouse striatum by 5-HT(1A) and 5-HT(1B) receptors. J Pharmacol Exp Ther. 2000 Mar;292(3):1111-7
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