FEMA-4809

CAS No. 1374760-95-8

FEMA-4809( —— )

Catalog No. M34249 CAS No. 1374760-95-8

FEMA-4809, a highly potent TRPM8 receptor activator, TRPM8 is the ion channel responsible for the cool perception.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 74 Get Quote
5MG 112 Get Quote
10MG 186 Get Quote
25MG 307 Get Quote
50MG 434 Get Quote
100MG 605 Get Quote
500MG 1197 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    FEMA-4809
  • Note
    Research use only, not for human use.
  • Brief Description
    FEMA-4809, a highly potent TRPM8 receptor activator, TRPM8 is the ion channel responsible for the cool perception.
  • Description
    FEMA 4809 is a TRPM8 receptor agonist (EC50=0.2 nM) for use as a cooling agent. TRPM8 is the ion channel responsible for the cool perception.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    TRP/TRPV Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1374760-95-8
  • Formula Weight
    327.4
  • Molecular Formula
    C17H17N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (763.59 mM; Ultrasonic )
  • SMILES
    Cc1ccc(OCC(=O)N(Cc2cccs2)c2cc[nH]n2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Alain Noncovich, et al. Discovery and development of a novel class of phenoxyacetyl amides as highly potent TRPM8 agonists for use as cooling agents. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3931-3938.?
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