MDK-6983
CAS No. 1227476-98-3
MDK-6983( Autophagy inhibitor 6k | Compound 6k | MDK-6983 | MDK 6983 | MDK6983 )
Catalog No. M27899 CAS No. 1227476-98-3
MDK-6983 is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 283 | In Stock |
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| 5MG | 249 | In Stock |
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| 10MG | 368 | In Stock |
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| 25MG | 562 | In Stock |
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| 50MG | 770 | In Stock |
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| 100MG | 1032 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMDK-6983
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NoteResearch use only, not for human use.
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Brief DescriptionMDK-6983 is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.
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DescriptionMDK-6983 is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.
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In Vitro——
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In Vivo——
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SynonymsAutophagy inhibitor 6k | Compound 6k | MDK-6983 | MDK 6983 | MDK6983
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PathwayAutophagy
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TargetAutophagy
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Recptormicrotubule
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Research Area——
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Indication——
Chemical Information
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CAS Number1227476-98-3
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Formula Weight429.3
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Molecular FormulaC22H18Cl2N2O3
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Purity>98% (HPLC)
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Solubility——
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SMILESOc1ccc(Cl)cc1C(=O)N[C@H](Cc1ccccc1)C(=O)Nc1ccc(Cl)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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CP-312
CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1 expression.
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Pitavastatin
Pitavastatin (NK-104) is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase, effectively inhibiting cholesterol synthesis from acetic acid in HepG2 cells with an IC50 of 5.8 nM.
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Lys05
Lys05 (Lys01 trihydrochloride, PS-1001)?is the water-soluble salt of Lys01, is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ); shows IC50 values of 3.6, 3.8, 6 and 7.9 uM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay.
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