Methyl 2,5-dihydroxycinnamate
CAS No. 63177-57-1
Methyl 2,5-dihydroxycinnamate( —— )
Catalog No. M27654 CAS No. 63177-57-1
Methyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 50 | Get Quote |
|
| 10MG | 87 | Get Quote |
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| 25MG | 177 | Get Quote |
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| 50MG | 335 | Get Quote |
|
| 100MG | 500 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMethyl 2,5-dihydroxycinnamate
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NoteResearch use only, not for human use.
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Brief DescriptionMethyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.
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DescriptionMethyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetEGFR
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RecptorApoptosis|BiP
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Research Area——
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Indication——
Chemical Information
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CAS Number63177-57-1
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Formula Weight194.186
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Molecular FormulaC10H10O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (643.73 mM)
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SMILESCOC(=O)\C=C\c1cc(O)ccc1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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AV-412
AV-412 is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).In cells, MP-412 inhibited autophosphorylation of EGFR and ErbB2 with IC(50) of 43 and 282 nM, respectively.?
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AZD8931 diFuMaric ac...
AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).AZD8931 significantly suppressed cell growth of IBC cells and induced apoptosis of human IBC cells in vitro.AZD8931 monotherapy inhibited xenograft growth.
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