Home - Products - Angiogenesis - EGFR - VUF 10166

VUF 10166

CAS No. 155584-74-0

VUF 10166( —— )

Catalog No. M17335 CAS No. 155584-74-0

VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	29	In Stock
10MG	38	In Stock
25MG	70	In Stock
50MG	111	In Stock
100MG	184	In Stock
200MG	275	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

VUF 10166
Note

Research use only, not for human use.
Brief Description

VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.
Description

VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

EGFR
Recptor

5-HT3A| 5-HT3AB
Research Area

Inflammation/Immunology
Indication

——

Chemical Information

CAS Number

155584-74-0
Formula Weight

262.74
Molecular Formula

C13H15ClN4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (380.60 mM)
SMILES

CN1CCN(CC1)C1=NC2=CC=CC=C2N=C1Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Thompson AJ, et al. J Pharmacol Exp Ther, 2012, 341(2), 350-9.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Daphnetin

Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activities.
AG-825

AG-825（Tyrphostin C15） is a selective and competitive ErbB2 inhibitor that inhibits tyrosine phosphorylation with an IC50 value of 0.35 μM.AG-825 (Tyrphostin C15) inhibits HER2 and shows anticancer activity in a mouse xenograft model of breast cancer.
Simotinib

Simotinib (SIM-6802) is a novel potent EGFR inhibitor for treatment of NSCLC.

Sign In Join Free