Cart
sales@molnova.com
MEDICA16
CAS No. 87272-20-6
MEDICA16( MEDICA 16 )
Catalog No. M27653 CAS No. 87272-20-6
MEDICA16 is a selective agonist for GPR40 as well as a partial agonist for GPR120.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 87 | Get Quote |
|
| 10MG | 132 | Get Quote |
|
| 25MG | 282 | Get Quote |
|
| 50MG | 484 | Get Quote |
|
| 100MG | 700 | Get Quote |
|
| 500MG | 1458 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameMEDICA16
-
NoteResearch use only, not for human use.
-
Brief DescriptionMEDICA16 is a selective agonist for GPR40 as well as a partial agonist for GPR120.
-
DescriptionMEDICA16 is a selective agonist for GPR40 as well as a partial agonist for GPR120. MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle with an increase in insulin sensitivity.
-
In Vitro——
-
In Vivo——
-
SynonymsMEDICA 16
-
PathwayCell Cycle/DNA Damage
-
TargetGPR
-
RecptorPHD3|HIF-2α|VEGFR1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number87272-20-6
-
Formula Weight342.52
-
Molecular FormulaC20H38O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (291.96 mM)
-
SMILESCC(C)(CCCCCCCCCCC(C)(C)CC(O)=O)CC(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Roda JM, et al. Stabilization of HIF-2α induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model. J Immunol. 2012 Sep 15;189(6):3168-77.
molnova catalog
related products
-
AMG 837 calcium hydr...
AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM).
-
ML 145
ML 145 is a selective and potent antagonist of human GPR35, with no significant activity against GPR35 in any of its immediate rodent homologs.
-
GLPG1205
GLPG1205 is a potent, orally active GPR84 (G protein-coupled receptor) antagonist with anti-inflammatory activity. GLPG1205 shows good PK/PD characteristics and can be used to study pulmonary fibrosis.
